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M94A0200.TXT
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1994-10-08
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Document 0200
DOCN M94A0200
TI Retinochoroiditis in the acquired immune deficiency syndrome. Findings
in consecutive post-mortem examinations.
DT 9412
AU Seregard S; Ophthalmic Pathology and Oncology Service, St Erik's Eye;
Hospital, Stockholm, Sweden.
SO Acta Ophthalmol (Copenh). 1994 Apr;72(2):223-8. Unique Identifier :
AIDSLINE MED/94360747
AB A number of opportunistic agents may cause retinitis or
retinochoroiditis in patients with the acquired immunodeficiency
syndrome. Minimal consecutive data is available on the
histopathologically confirmed prevalence of these ocular infections. A
total of 48 consecutive patients with acquired immunodeficiency
syndrome-related death underwent autopsy and had their eyes submitted
for histopathological examination. Conventional light microscopy
combined with immunohistochemistry revealed cytomegalovirus retinitis in
15 patients, toxoplasma gonddi retinochoroiditis in 3 patients and
mycobacterial choroiditis in one individual with some infections being
coexistent. Clinical examination prior to death was highly accurate in
detecting cytomegalovirus retinitis, but failed to determine all
non-cytomegalovirus causes of retinochoroiditis. Ten of 15 patients with
cytomegalovirus retinitis had associated non-cular cytomegalovirus
infections, most often in the brain and adrenals. After clinical
detection of cytomegalovirus retinitis the median survival time was 5.5
months, not adversely affected by additional non-ocular cytomegalovirus
infection.
DE Adult Aged Aged, 80 and over AIDS-Related Opportunistic
Infections/*PATHOLOGY Chorioretinitis/MICROBIOLOGY/*PATHOLOGY
Cytomegalovirus Retinitis/PATHOLOGY Eye Infections/*PATHOLOGY Female
Human *HIV-1 Male Middle Age Mycobacterium avium-intracellulare
Infection/PATHOLOGY Prevalence Support, Non-U.S. Gov't Toxoplasmosis,
Ocular/PATHOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).